International Circulation: We’re here with Doctor Mehran; Doctor, what are your thoughts about the long-term safety of sirolimus eluting stents compared with bare-metal stents?
国际循环: 和普通金属支架相比,您觉得西罗莫司洗脱支架长期安全性如何?
Prof. Roxana Mehran: Well, so far based on the data that we have – and we now have at least five-year data from large randomized clinical trials – there donot appear to be any safety issues whatsoever that concern me. In fact, I feel that the sirolimus-eluting stent—the Cypher stent—is really the most durable one. We have the most information on that stent and on the paclitaxel-eluting Taxus stent. These are the first-generation of drug-eluting stents. We have the luxury of having very long-term data on both the safety and efficacy of these stents.
Prof. Roxana Mehran: 根据现有的资料,目前我们有关于大型随机临床试验至少5年的研究资料,似乎没有任何我们所担心的安全问题。事实上我认为西罗莫司洗脱支架,Cypher支架是真正最耐久的支架,我们有关于该支架大量的研究资料,或者紫杉醇洗脱;这些都是第一代药物洗脱支架。我们有大量关于长期安全性和疗效的资料。
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